2. Round
22/10/2021 16:00 Rio Ave FC Rio Ave FC - Sporting Braga Sporting Braga -:-
6. Round
20/10/2021 11:00 Vitória Guimarães Vitória Guimarães - FC Vizela FC Vizela -:-
7. Round
14/10/2021 11:00 FC Vizela FC Vizela - FC Famalicão FC Famalicão
15/10/2021 11:00 Rio Ave FC Rio Ave FC - Vitória Guimarães Vitória Guimarães
16/10/2021 11:00 GD Estoril GD Estoril - Belenenses SAD Belenenses SAD
16/10/2021 11:00 Portimonense SC Portimonense SC - CS Marítimo CS Marítimo
16/10/2021 15:00 Académica de Coimbra Académica de Coimbra - Leixões SC Leixões SC
24/10/2021 11:00 Sporting CP Sporting CP - SL Benfica SL Benfica -:-
8. Round
28/10/2021 11:00 Sporting CP Sporting CP - CS Marítimo CS Marítimo -:-
28/10/2021 15:00 Rio Ave FC Rio Ave FC - FC Famalicão FC Famalicão -:-
29/10/2021 11:00 FC Vizela FC Vizela - Sporting Braga Sporting Braga -:-
30/10/2021 11:00 Académica de Coimbra Académica de Coimbra - Vitória Guimarães Vitória Guimarães -:-
30/10/2021 11:00 GD Estoril GD Estoril - SC Farense SC Farense -:-
30/10/2021 11:00 Portimonense SC Portimonense SC - Belenenses SAD Belenenses SAD -:-