| 1. Round | 06/08/2022 | Vysočina Jihlava [Youth B] | - | 1. FC Slovácko [Youth B] | 2:1 | ||||
| 4. Round | 27/08/2022 | 1. FC Slovácko [Youth B] | - | Dynamo České Budějovice [Youth B] | 4:0 | ||||
| 6. Round | 10/09/2022 | AC Sparta Praha [Youth B] | - | 1. FC Slovácko [Youth B] | 3:0 | ||||
| 9. Round | 01/10/2022 | 1. FC Slovácko [Youth B] | - | FC Zbrojovka Brno [Youth B] | 0:2 | ||||
| 11. Round | 14/10/2022 | 1. FC Slovácko [Youth B] | - | FK Dukla Praha [Youth B] | 1:1 | ||||
| 12. Round | 21/10/2022 | MFK Karviná [Youth B] | - | 1. FC Slovácko [Youth B] | 0:3 | ||||
| 14. Round | 26/10/2022 | FC Zlín [Youth B] | - | 1. FC Slovácko [Youth B] | 1:1 | ||||
| 22. Round | 15/04/2023 | FK Mladá Boleslav [Youth B] | - | 1. FC Slovácko [Youth B] | 2:0 | ||||
| 24. Round | 29/04/2023 | FC Zbrojovka Brno [Youth B] | - | 1. FC Slovácko [Youth B] | 2:1 | ||||
| 26. Round | 12/05/2023 | FK Dukla Praha [Youth B] | - | 1. FC Slovácko [Youth B] | 1:1 | ||||
| 27. Round | 20/05/2023 | 1. FC Slovácko [Youth B] | - | MFK Karviná [Youth B] | 4:0 | ||||
| 28. Round | 27/05/2023 | FK Příbram [Youth B] | - | 1. FC Slovácko [Youth B] | 3:3 | ||||
| 29. Round | 03/06/2023 | 1. FC Slovácko [Youth B] | - | FC Zlín [Youth B] | 5:5 |
Czech Republic