| 1. Round | 15/08/2015 | River Plate | - | Fénix | 1:2 |  |
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| 5. Round | 13/09/2015 | River Plate | - | Racing | 3:1 | ||||
| 6. Round | 20/09/2015 | Plaza Colonia | - | River Plate | 3:2 | ||||
| 7. Round | 27/09/2015 | River Plate | - | Peñarol | 4:0 | ||||
| 8. Round | 04/10/2015 | Juventud de Las Piedras | - | River Plate | 2:3 | |
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| 9. Round | 18/10/2015 | River Plate | - | Danubio | 2:1 | |
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| 10. Round | 25/10/2015 | CA Cerro | - | River Plate | 1:1 | |
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| 11. Round | 01/11/2015 | River Plate | - | Rentistas | 2:3 |
Uruguay