| 3. Round | 22/09/2019 | River Plate | - | Boston River | 1:4 | ||||
| 4. Round | 05/10/2019 | Danubio | - | River Plate | 1:1 | ||||
| 5. Round | 09/10/2019 | River Plate | - | Plaza Colonia | 0:0 |  |
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| 6. Round | 16/10/2019 | CA Cerro | - | River Plate | 3:2 | ||||
| 10. Round | 06/11/2019 | River Plate | - | Progreso | 1:2 | |
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| 11. Round | 09/11/2019 | Peñarol | - | River Plate | 1:0 | ||||
| 12. Round | 16/11/2019 | River Plate | - | Defensor Sporting | 1:0 | ||||
| 13. Round | 22/11/2019 | Rampla Juniors | - | River Plate | 2:2 | ||||
| 14. Round | 27/11/2019 | River Plate | - | Juventud de Las Piedras | 1:0 |
Uruguay