| 1. Round | 12/02/2021 | San Lorenzo II | - | Arsenal de Sarandí II | 3:0 | ||||
| 2. Round | 19/02/2021 | Colón de Santa Fe II | - | San Lorenzo II | 1:1 | ||||
| 8. Round | 02/04/2021 | San Lorenzo II | - | Rosario Central II | 0:0 | ||||
| 9. Round | 09/04/2021 | Platense II | - | San Lorenzo II | 2:0 | ||||
| 10. Round | 16/04/2021 | San Lorenzo II | - | Argentinos Juniors II | 2:2 | ||||
| 11. Round | 23/04/2021 | River Plate II | - | San Lorenzo II | 2:1 |
Argentina