1. Round | 05/06/2022 | Independiente II | - | San Lorenzo II | 0:1 | ||||
4. Round | 20/06/2022 | San Lorenzo II | - | Central Córdoba SdE II | 0:0 | ||||
5. Round | 25/06/2022 | Tigre II | - | San Lorenzo II | 3:2 | ||||
6. Round | 03/07/2022 | San Lorenzo II | - | Barracas Central II | 1:0 | ||||
7. Round | 08/07/2022 | Boca Juniors II | - | San Lorenzo II | 2:1 | ||||
8. Round | 13/07/2022 | San Lorenzo II | - | Banfield II | 0:1 | ||||
16. Round | 28/08/2022 | Rosario Central II | - | San Lorenzo II | 0:1 | ||||
22. Round | 28/09/2022 | Huracán II | - | San Lorenzo II | 3:1 |