1. Round | 06/01/2022 | Atlético San Luis [U20] | - | CF Pachuca [U20] | 0:2 | ||||
2. Round | 15/01/2022 | Atlas Guadalajara [U20] | - | Atlético San Luis [U20] | 1:3 | ||||
4. Round | 05/02/2022 | CF América [U20] | - | Atlético San Luis [U20] | 0:1 | ||||
5. Round | 12/02/2022 | Atlético San Luis [U20] | - | Deportivo Toluca [U20] | 4:1 | ||||
6. Round | 19/02/2022 | UANL Tigres [U20] | - | Atlético San Luis [U20] | 1:1 | ||||
10. Round | 13/03/2022 | Atlético San Luis [U20] | - | Puebla FC [U20] | 3:1 | ||||
11. Round | 17/03/2022 | Gallos Blancos [U20] | - | Atlético San Luis [U20] | 3:0 | ||||
12. Round | 01/04/2022 | Atlético San Luis [U20] | - | Mazatlán FC [U20] | 1:2 | ||||
9. Round | 06/04/2022 | Club Tijuana [U20] | - | Atlético San Luis [U20] | 2:1 | ||||
13. Round | 09/04/2022 | Atlético San Luis [U20] | - | Club León [U20] | 1:1 | ||||
14. Round | 15/04/2022 | Club Necaxa [U20] | - | Atlético San Luis [U20] | 3:0 | ||||
15. Round | 20/04/2022 | Atlético San Luis [U20] | - | Pumas UNAM [U20] | 2:1 | ||||
16. Round | 24/04/2022 | Cruz Azul [U20] | - | Atlético San Luis [U20] | 2:2 | ||||
17. Round | 01/05/2022 | Atlético San Luis [U20] | - | Santos Laguna [U20] | 2:2 |