10. Round | 05/09/2021 | Platense II | - | San Lorenzo II | 1:1 | ||||
15. Round | 11/10/2021 | San Lorenzo II | - | Colón de Santa Fe II | 1:1 | ||||
16. Round | 15/10/2021 | River Plate II | - | San Lorenzo II | 1:3 | ||||
3. Round | 11/11/2021 | Boca Juniors II | - | San Lorenzo II | 4:1 | ||||
24. Round | 06/12/2021 | Independiente II | - | San Lorenzo II | 1:0 |