| 1. Round | 04/09/2021 | Sporting Braga [U23] | - | FC Vizela [U23] | 3:1 |  |
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| 3. Round | 14/09/2021 | Sporting Braga [U23] | - | Académica de Coimbra [U23] | 2:0 | ||||
| 4. Round | 21/09/2021 | Leixões SC [U23] | - | Sporting Braga [U23] | 0:1 | ||||
| 5. Round | 27/09/2021 | Sporting Braga [U23] | - | Vitória Guimarães [U23] | 2:1 | |
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| 6. Round | 02/10/2021 | FC Famalicão [U23] | - | Sporting Braga [U23] | 1:0 | ||||
| 2. Round | 22/10/2021 | Rio Ave FC [U23] | - | Sporting Braga [U23] | 0:0 | ||||
| 8. Round | 29/10/2021 | FC Vizela [U23] | - | Sporting Braga [U23] | 0:3 | ||||
| 9. Round | 05/11/2021 | Sporting Braga [U23] | - | Rio Ave FC [U23] | 5:1 | |
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| 10. Round | 20/11/2021 | Académica de Coimbra [U23] | - | Sporting Braga [U23] | 1:2 | |
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| 11. Round | 27/11/2021 | Sporting Braga [U23] | - | Leixões SC [U23] | 3:0 | ||||
| 12. Round | 03/12/2021 | Vitória Guimarães [U23] | - | Sporting Braga [U23] | 0:2 | ||||
| 13. Round | 11/12/2021 | Sporting Braga [U23] | - | FC Famalicão [U23] | 1:1 |
Portugal