| 2. Round | 05/09/2021 | AC Ajaccio [Youth B] | - | OGC Nice [Youth B] | 2:0 | ||||
| 3. Round | 11/09/2021 | OGC Nice [Youth B] | - | Racing FC Toulon [Youth B] | 5:2 | ||||
| 7. Round | 09/10/2021 | OGC Nice [Youth B] | - | Castelnau Le Crès FC [Youth B] | 1:4 | ||||
| 9. Round | 23/10/2021 | SC Air Bel [Youth B] | - | OGC Nice [Youth B] | 4:2 | ||||
| 10. Round | 13/11/2021 | OGC Nice [Youth B] | - | AS Monaco [Youth B] | 0:1 | ||||
| 11. Round | 20/11/2021 | Gazélec FC Ajaccio [Youth B] | - | OGC Nice [Youth B] | 1:0 | ||||
| 13. Round | 04/12/2021 | Olympique Marseille [Youth B] | - | OGC Nice [Youth B] | 4:0 | ||||
| 14. Round | 15/01/2022 | OGC Nice [Youth B] | - | AC Ajaccio [Youth B] | 1:1 | ||||
| 15. Round | 22/01/2022 | Racing FC Toulon [Youth B] | - | OGC Nice [Youth B] | 1:1 | ||||
| 16. Round | 06/02/2022 | OGC Nice [Youth B] | - | Lyon-La Duchère [Youth B] | 1:1 | ||||
| 17. Round | 12/02/2022 | AS Saint-Étienne [Youth B] | - | OGC Nice [Youth B] | 2:2 | ||||
| 18. Round | 05/03/2022 | OGC Nice [Youth B] | - | AS Saint-Priest [Youth B] | 1:0 | ||||
| 20. Round | 19/03/2022 | Clermont Foot 63 [Youth B] | - | OGC Nice [Youth B] | 1:2 | ||||
| 21. Round | 26/03/2022 | OGC Nice [Youth B] | - | SC Air Bel [Youth B] | 3:2 |
France
Guadeloupe