| 19. Round | 05/02/2021 | Neuchâtel Xamax FCS | - | FC Thun | 0:3 | ||||
| 21. Round | 20/02/2021 | Neuchâtel Xamax FCS | - | FC Winterthur | 3:1 | ||||
| 20. Round | 23/02/2021 | FC Aarau | - | Neuchâtel Xamax FCS | 4:0 | ||||
| 22. Round | 26/02/2021 | SC Kriens | - | Neuchâtel Xamax FCS | 1:1 | ||||
| 23. Round | 02/03/2021 | Neuchâtel Xamax FCS | - | FC Chiasso | 2:1 | ||||
| 24. Round | 05/03/2021 | FC Wil 1900 | - | Neuchâtel Xamax FCS | 1:0 | ||||
| 25. Round | 12/03/2021 | Neuchâtel Xamax FCS | - | FC Schaffhausen | 3:0 |  |
|||
| 26. Round | 19/03/2021 | Neuchâtel Xamax FCS | - | Stade Lausanne-Ouchy | 0:0 |  |
|||
| 28. Round | 10/04/2021 | Neuchâtel Xamax FCS | - | FC Aarau | 0:1 | ||||
| 29. Round | 16/04/2021 | FC Thun | - | Neuchâtel Xamax FCS | 0:0 | ||||
| 30. Round | 20/04/2021 | Neuchâtel Xamax FCS | - | SC Kriens | 0:3 | ||||
| 33. Round | 07/05/2021 | Neuchâtel Xamax FCS | - | FC Wil 1900 | 2:2 | |
|||
| 34. Round | 10/05/2021 | Stade Lausanne-Ouchy | - | Neuchâtel Xamax FCS | 1:1 | ||||
| 35. Round | 14/05/2021 | Neuchâtel Xamax FCS | - | Grasshopper Club Zürich | 1:1 | ||||
| 36. Round | 20/05/2021 | FC Chiasso | - | Neuchâtel Xamax FCS | 2:1 | |
Congo DR