| 1. Round | 16/08/2001 | Talleres de Córdoba | - | River Plate | 1:3 | ||||
| 2. Round | 25/08/2001 | River Plate | - | Huracán | 4:1 |  |
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| 3. Round | 28/08/2001 | Unión de Santa Fe | - | River Plate | 1:1 | ||||
| 4. Round | 01/09/2001 | River Plate | - | Estudiantes | 3:0 |  |
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| 5. Round | 08/09/2001 | Nueva Chicago | - | River Plate | 2:1 | ||||
| 6. Round | 15/09/2001 | River Plate | - | Boca Juniors | 1:1 |  |
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| 8. Round | 29/09/2001 | River Plate | - | Vélez Sarsfield | 4:2 | |
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| 9. Round | 02/10/2001 | Independiente | - | River Plate | 0:5 | |
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| 10. Round | 20/10/2001 | River Plate | - | Newell's Old Boys | 2:0 | ||||
| 11. Round | 27/10/2001 | Belgrano de Córdoba | - | River Plate | 0:2 | |
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| 12. Round | 03/11/2001 | River Plate | - | San Lorenzo | 2:2 | ||||
| 13. Round | 10/11/2001 | Colón de Santa Fe | - | River Plate | 1:0 | ||||
| 14. Round | 17/11/2001 | River Plate | - | Gimnasia de La Plata | 4:0 | ||||
| 15. Round | 24/11/2001 | Chacarita Juniors | - | River Plate | 1:4 | |
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| 16. Round | 01/12/2001 | Racing Club | - | River Plate | 1:1 | |
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| 17. Round | 08/12/2001 | River Plate | - | Lanús | 4:0 | |
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| 18. Round | 15/12/2001 | Argentinos Juniors | - | River Plate | 1:3 | ||||
| 19. Round | 26/12/2001 | River Plate | - | Rosario Central | 6:1 |
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