| 1. Round | 06/08/2022 | FC Zlín [Youth B] | - | Viktoria Plzeň [Youth B] | 1:1 | ||||
| 2. Round | 12/08/2022 | FC Zbrojovka Brno [Youth B] | - | FC Zlín [Youth B] | 2:2 | ||||
| 3. Round | 16/08/2022 | FC Zlín [Youth B] | - | Slavia Praha [Youth B] | 2:3 | ||||
| 4. Round | 27/08/2022 | FK Dukla Praha [Youth B] | - | FC Zlín [Youth B] | 1:1 | ||||
| 8. Round | 30/08/2022 | FC Zlín [Youth B] | - | FC Hradec Králové [Youth B] | 2:1 | ||||
| 5. Round | 03/09/2022 | FC Zlín [Youth B] | - | MFK Karviná [Youth B] | 3:0 | ||||
| 6. Round | 10/09/2022 | FK Příbram [Youth B] | - | FC Zlín [Youth B] | 1:3 | ||||
| 9. Round | 01/10/2022 | Vysočina Jihlava [Youth B] | - | FC Zlín [Youth B] | 3:2 | ||||
| 10. Round | 08/10/2022 | FC Zlín [Youth B] | - | FK Pardubice [Youth B] | 1:3 | ||||
| 11. Round | 14/10/2022 | Banik Ostrava [Youth B] | - | FC Zlín [Youth B] | 3:1 | ||||
| 12. Round | 22/10/2022 | FC Zlín [Youth B] | - | Dynamo České Budějovice [Youth B] | 4:3 | ||||
| 13. Round | 29/10/2022 | Sigma Olomouc [Youth B] | - | FC Zlín [Youth B] | 5:2 |  |
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| 15. Round | 12/11/2022 | FK Mladá Boleslav [Youth B] | - | FC Zlín [Youth B] | 2:1 | ||||
| 28. Round | 27/05/2023 | FC Zlín [Youth B] | - | Sigma Olomouc [Youth B] | 0:2 |
Ukraine