| Qual. 2. Round | 17/10/2021 | Hearts of Oak | - | Wydad AC | 1:0 | ||||
| Qual. 2. Round | 24/10/2021 | Wydad AC | - | Hearts of Oak | 6:1 |  |
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| Group D | 26/02/2022 | Wydad AC | - | Zamalek | 3:1 | ||||
| Group D | 11/03/2022 | Zamalek | - | Wydad AC | 0:1 | ||||
| Group D | 19/03/2022 | GD Sagrada Esperança | - | Wydad AC | 1:2 | ||||
| Group D | 02/04/2022 | Wydad AC | - | Petro Atlético | 5:1 | ||||
| Quarter-finals | 16/04/2022 | CR Bélouizdad | - | Wydad AC | 0:1 | ||||
| Quarter-finals | 23/04/2022 | Wydad AC | - | CR Bélouizdad | 0:0 | ||||
| Semi-finals | 07/05/2022 | Petro Atlético | - | Wydad AC | 1:3 | ||||
| Semi-finals | 13/05/2022 | Wydad AC | - | Petro Atlético | 1:1 | ||||
| Final | 30/05/2022 | Wydad AC | - | Al Ahly SC | 2:0 |
Morocco