| 5. Round | 10/10/2021 | Paris Saint-Germain [Women] | - | EA Guingamp [Women] | 6:0 | ||||
| 6. Round | 17/10/2021 | Paris Saint-Germain [Women] | - | AS Saint-Étienne [Women] | 2:0 | ||||
| 7. Round | 31/10/2021 | Dijon FCO [Women] | - | Paris Saint-Germain [Women] | 0:3 | ||||
| 8. Round | 14/11/2021 | Olympique Lyonnais [Women] | - | Paris Saint-Germain [Women] | 6:1 | ||||
| 11. Round | 12/12/2021 | Paris Saint-Germain [Women] | - | Girondins Bordeaux [Women] | 1:0 | ||||
| 13. Round | 23/01/2022 | AS Saint-Étienne [Women] | - | Paris Saint-Germain [Women] | 0:5 | ||||
| 14. Round | 05/02/2022 | EA Guingamp [Women] | - | Paris Saint-Germain [Women] | 2:6 | ||||
| 12. Round | 11/02/2022 | Paris Saint-Germain [Women] | - | Dijon FCO [Women] | 5:0 | ||||
| 15. Round | 27/02/2022 | FC Fleury 91 [Women] | - | Paris Saint-Germain [Women] | 0:4 | ||||
| 16. Round | 11/03/2022 | Paris Saint-Germain [Women] | - | Montpellier HSC [Women] | 0:0 | ||||
| 18. Round | 03/04/2022 | Paris FC [Women] | - | Paris Saint-Germain [Women] | 0:0 |  |
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| 19. Round | 16/04/2022 | Paris Saint-Germain [Women] | - | GPSO 92 Issy [Women] | 6:1 |
Czech Republic