| 2. Round | 23/06/2021 | San Antonio Unido | - | Huachipato | 0:0 | ||||
| 2. Round | 26/06/2021 | Huachipato | - | San Antonio Unido | 3:2 | ||||
| Round of 16 | 01/07/2021 | Deportes Temuco | - | Huachipato | 2:2 | ||||
| Round of 16 | 05/07/2021 | Huachipato | - | Deportes Temuco | 2:0 |  |
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| Quarter-finals | 05/08/2021 | Unión Española | - | Huachipato | 1:1 |
Chile