| 4. Round | 24/07/2022 | Atlético Junior | - | Santa Fe | 2:0 | ||||
| 6. Round | 08/08/2022 | Atlético Junior | - | Once Caldas | 1:2 | ||||
| 7. Round | 14/08/2022 | Atlético Junior | - | Independiente Medellín | 4:2 |  |
 |
||
| 8. Round | 21/08/2022 | América de Cali | - | Atlético Junior | 2:1 | ||||
| 9. Round | 29/08/2022 | Atlético Junior | - | Deportes Tolima | 2:1 | ||||
| 10. Round | 04/09/2022 | Unión Magdalena | - | Atlético Junior | 2:1 |  |
 |
||
| 12. Round | 18/09/2022 | Deportivo Pasto | - | Atlético Junior | 2:1 | ||||
| 13. Round | 22/09/2022 | Atlético Junior | - | Millonarios | 0:1 | |
|||
| 19. Round | 24/10/2022 | Atlético Junior | - | Cortuluá | 2:1 | ||||
| 20. Round | 30/10/2022 | Jaguares de Córdoba | - | Atlético Junior | 0:2 |
Colombia