| 27. Round | 04/04/2021 | 1. FC Nürnberg | - | SC Paderborn 07 | 2:1 | ||||
| 28. Round | 10/04/2021 | SC Paderborn 07 | - | VfL Bochum | 3:0 | ||||
| 29. Round | 16/04/2021 | Eintracht Braunschweig | - | SC Paderborn 07 | 0:0 | ||||
| 30. Round | 21/04/2021 | SC Paderborn 07 | - | VfL Osnabrück | 2:2 | ||||
| 31. Round | 24/04/2021 | SC Paderborn 07 | - | Fortuna Düsseldorf | 2:1 | ||||
| 32. Round | 09/05/2021 | Erzgebirge Aue | - | SC Paderborn 07 | 3:8 |  |
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| 33. Round | 16/05/2021 | SC Paderborn 07 | - | SpVgg Greuther Fürth | 2:4 | ||||
| 34. Round | 23/05/2021 | Würzburger Kickers | - | SC Paderborn 07 | 1:1 |
Congo DR