| 2. Round | 09/06/2022 | Atlético Tucumán II | - | River Plate II | 1:0 | ||||
| 3. Round | 14/06/2022 | Lanús II | - | Atlético Tucumán II | 2:4 | ||||
| 6. Round | 03/07/2022 | Atlético Tucumán II | - | Vélez Sarsfield II | 1:0 | ||||
| 7. Round | 08/07/2022 | Gimnasia de La Plata II | - | Atlético Tucumán II | 1:1 | ||||
| 10. Round | 23/07/2022 | Atlético Tucumán II | - | Independiente II | 1:2 | ||||
| 11. Round | 28/07/2022 | Newell's Old Boys II | - | Atlético Tucumán II | 0:0 | ||||
| 14. Round | 17/08/2022 | Atlético Tucumán II | - | Tigre II | 2:0 | ||||
| 15. Round | 21/08/2022 | Barracas Central II | - | Atlético Tucumán II | 2:0 | ||||
| 16. Round | 29/08/2022 | Atlético Tucumán II | - | Boca Juniors II | 1:2 | ||||
| 19. Round | 12/09/2022 | Talleres de Córdoba II | - | Atlético Tucumán II | 3:1 | ||||
| 20. Round | 19/09/2022 | Atlético Tucumán II | - | Argentinos Juniors II | 1:1 | ||||
| 23. Round | 03/10/2022 | Platense II | - | Atlético Tucumán II | 3:0 | ||||
| 27. Round | 21/10/2022 | Atlético Tucumán II | - | Defensa y Justicia II | 1:0 |
Argentina