| 3. Round | 19/08/2022 | FK Příbram [Youth B] | - | FK Dukla Praha [Youth B] | 1:2 | ||||
| 4. Round | 27/08/2022 | FK Dukla Praha [Youth B] | - | FC Zlín [Youth B] | 1:1 | ||||
| 8. Round | 30/08/2022 | FK Dukla Praha [Youth B] | - | Banik Ostrava [Youth B] | 0:6 | ||||
| 5. Round | 03/09/2022 | FC Hradec Králové [Youth B] | - | FK Dukla Praha [Youth B] | 2:1 | ||||
| 6. Round | 09/09/2022 | FK Dukla Praha [Youth B] | - | Vysočina Jihlava [Youth B] | 2:3 | ||||
| 7. Round | 17/09/2022 | FK Pardubice [Youth B] | - | FK Dukla Praha [Youth B] | 4:1 | ||||
| 11. Round | 14/10/2022 | 1. FC Slovácko [Youth B] | - | FK Dukla Praha [Youth B] | 1:1 | ||||
| 12. Round | 22/10/2022 | FK Dukla Praha [Youth B] | - | FK Mladá Boleslav [Youth B] | 3:1 | ||||
| 13. Round | 28/10/2022 | Viktoria Plzeň [Youth B] | - | FK Dukla Praha [Youth B] | 2:3 | ||||
| 14. Round | 05/11/2022 | FC Zbrojovka Brno [Youth B] | - | FK Dukla Praha [Youth B] | 6:1 | ||||
| 15. Round | 12/11/2022 | Slavia Praha [Youth B] | - | FK Dukla Praha [Youth B] | 2:3 |  |
Czech Republic