8. Round | 19/09/2021 | Royal Antwerp FC | - | RFC Seraing | 2:1 | ||||
9. Round | 26/09/2021 | KRC Genk | - | RFC Seraing | 3:0 | ||||
10. Round | 03/10/2021 | RFC Seraing | - | SV Zulte Waregem | 5:1 | ||||
11. Round | 16/10/2021 | Union Saint-Gilloise | - | RFC Seraing | 4:2 | ||||
13. Round | 30/10/2021 | K Beerschot VA | - | RFC Seraing | 3:0 | ||||
14. Round | 07/11/2021 | RFC Seraing | - | KAA Gent | 0:0 | ||||
15. Round | 20/11/2021 | Oud-Heverlee Leuven | - | RFC Seraing | 1:3 | ||||
16. Round | 27/11/2021 | RFC Seraing | - | Sint-Truidense VV | 2:0 | ||||
17. Round | 04/12/2021 | Club Brugge KV | - | RFC Seraing | 3:2 | ||||
18. Round | 11/12/2021 | RFC Seraing | - | RSC Anderlecht | 0:5 | ||||
19. Round | 14/12/2021 | Cercle Brugge | - | RFC Seraing | 2:0 | ||||
20. Round | 17/12/2021 | RFC Seraing | - | KV Kortrijk | 0:2 | ||||
21. Round | 27/12/2021 | KV Mechelen | - | RFC Seraing | 2:0 | ||||
22. Round | 18/01/2022 | RFC Seraing | - | Union Saint-Gilloise | 0:4 |