| 1. Round | 27/08/2005 | Skoda Xanthi | - | PAOK Saloniki | 1:0 | ||||
| 2. Round | 11/09/2005 | OFI Heraklion | - | Skoda Xanthi | 1:1 | ||||
| 3. Round | 18/09/2005 | Skoda Xanthi | - | Apollon Kalamarias | 2:0 | ||||
| 5. Round | 03/10/2005 | Atromitos | - | Skoda Xanthi | 0:1 | ||||
| 6. Round | 17/10/2005 | Skoda Xanthi | - | Iraklis Saloniki | 4:1 | ||||
| 10. Round | 19/11/2005 | Skoda Xanthi | - | Ionikos Nikea | 1:1 | ||||
| 12. Round | 05/12/2005 | Panionios GSS | - | Skoda Xanthi | 0:2 | ||||
| 13. Round | 11/12/2005 | Skoda Xanthi | - | GS Kallithea | 2:2 | ||||
| 14. Round | 19/12/2005 | Akratitos Liosion | - | Skoda Xanthi | 2:0 |
Czech Republic