| 5. Round | 04/08/2000 | Servette FC | - | Neuchâtel Xamax FC | 5:2 | ||||
| 6. Round | 12/08/2000 | Neuchâtel Xamax FC | - | FC St. Gallen | 2:1 | ||||
| 7. Round | 19/08/2000 | FC Lugano | - | Neuchâtel Xamax FC | 3:0 | ||||
| 9. Round | 05/09/2000 | FC Zürich | - | Neuchâtel Xamax FC | 3:0 | ||||
| 10. Round | 09/09/2000 | Neuchâtel Xamax FC | - | Lausanne Sports | 2:4 | ||||
| 14. Round | 14/10/2000 | Neuchâtel Xamax FC | - | Grasshopper Club Zürich | 1:3 | ||||
| 15. Round | 21/10/2000 | Yverdon Sport FC | - | Neuchâtel Xamax FC | 4:0 | ||||
| 16. Round | 29/10/2000 | Neuchâtel Xamax FC | - | Servette FC | 2:1 | ||||
| 18. Round | 05/11/2000 | Neuchâtel Xamax FC | - | FC Lugano | 1:0 | ||||
| 17. Round | 12/11/2000 | FC St. Gallen | - | Neuchâtel Xamax FC | 2:0 | ||||
| 19. Round | 19/11/2000 | FC Aarau | - | Neuchâtel Xamax FC | 2:0 |  |
France