| 2. Round | 24/07/2021 | FK Strogino Moskva | - | FK Saransk | 1:1 | ||||
| 6. Round | 21/08/2021 | FK Saransk | - | Kvant Obninsk | 3:0 | ||||
| 9. Round | 10/09/2021 | FK Peresvet Podolsk | - | FK Saransk | 2:0 | ||||
| 18. Round | 25/10/2021 | Rodina Moskva | - | FK Saransk | 3:1 | ||||
| 20. Round | 04/11/2021 | Metallurg Vidnoye | - | FK Saransk | 1:3 |  |
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| 21. Round | 10/11/2021 | FK Saransk | - | FK Saturn | 2:0 | ||||
| 22. Round | 14/11/2021 | FK Khimki 2 | - | FK Saransk | 1:2 |
Russia