1. Round | 19/09/2021 | Colima FC | - | Mazorqueros | 1:2 | ||||
2. Round | 25/09/2021 | Mazorqueros | - | Leones Negros II | 3:0 | ![]() |
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3. Round | 05/10/2021 | Coras de Nayarit | - | Mazorqueros | 0:2 | ![]() |
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4. Round | 09/10/2021 | Mazorqueros | - | Mineros de Fresnillo FC | 0:0 | ||||
5. Round | 14/10/2021 | Tuzos de la UAZ | - | Mazorqueros | 2:4 | ![]() |
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6. Round | 17/10/2021 | Mazorqueros | - | Alacranes de Durango | 1:1 | ||||
7. Round | 23/10/2021 | Cimarrones de Sonora II | - | Mazorqueros | 1:2 | ||||
8. Round | 30/10/2021 | Mazorqueros | - | Saltillo FC | 1:2 | ||||
13. Round | 27/11/2021 | Mazorqueros | - | Tecos Fútbol Club | 3:0 |