| Group F | 28/04/2022 | Antofagasta | - | Atlético Goianiense | 2:1 |  |
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| Group F | 04/05/2022 | Atlético Goianiense | - | Defensa y Justicia | 3:2 | ||||
| Group F | 18/05/2022 | Atlético Goianiense | - | Antofagasta | 1:0 | ||||
| Group F | 25/05/2022 | LDU Quito | - | Atlético Goianiense | 1:1 | ||||
| Round of 16 | 01/07/2022 | Club Olimpia | - | Atlético Goianiense | 2:0 | ||||
| Quarter-finals | 02/08/2022 | Nacional | - | Atlético Goianiense | 0:1 | ||||
| Quarter-finals | 09/08/2022 | Atlético Goianiense | - | Nacional | 3:0 | ||||
| Semi-finals | 02/09/2022 | Atlético Goianiense | - | São Paulo FC | 3:1 | |
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| Semi-finals | 09/09/2022 | São Paulo FC | - | Atlético Goianiense | 4:2 pso |
Brazil