| Group 2 | 08/04/1980 | Nacional | - | Defensor Sporting | 1:0 | ||||
| Group 2 | 12/04/1980 | Oriente Petrolero | - | Nacional | 1:3 |  |
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| Group 2 | 16/04/1980 | The Strongest | - | Nacional | 3:0 | ||||
| Group 2 | 22/04/1980 | Defensor Sporting | - | Nacional | 0:3 | ||||
| Group 2 | 29/04/1980 | Nacional | - | The Strongest | 2:0 | ||||
| Group B | 20/05/1980 | O'Higgins | - | Nacional | 0:1 | ||||
| Group B | 17/06/1980 | Club Olimpia | - | Nacional | 0:1 | ||||
| Group B | 01/07/1980 | Nacional | - | Club Olimpia | 1:1 | |
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| Group B | 15/07/1980 | Nacional | - | O'Higgins | 2:0 | |
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| Final | 29/07/1980 | Internacional | - | Nacional | 0:0 | ||||
| Final | 05/08/1980 | Nacional | - | Internacional | 1:0 |
Uruguay