| 1. Round | 16/10/2020 | Universidad Catolica | - | Macará | 2:1 |  |
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| 2. Round | 19/10/2020 | Macará | - | Olmedo | 1:0 |  |
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| 3. Round | 24/10/2020 | Emelec | - | Macará | 0:0 | ||||
| 4. Round | 02/11/2020 | Macará | - | Guayaquil City | 1:1 | |
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| 5. Round | 05/11/2020 | Macará | - | Mushuc Runa | 0:3 | ||||
| 7. Round | 14/11/2020 | Macará | - | Orense SC | 0:1 | ||||
| 9. Round | 23/11/2020 | Macará | - | Liga de Portoviejo | 1:0 | |
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| 10. Round | 29/11/2020 | Barcelona | - | Macará | 3:0 | ||||
| 13. Round | 13/12/2020 | Macará | - | LDU Quito | 3:4 | ||||
| 14. Round | 18/12/2020 | El Nacional | - | Macará | 2:1 |
Venezuela
Colombia