| 1. Round | 08/01/2022 | CF Monterrey [U20] | - | Gallos Blancos [U20] | 0:0 | ||||
| 2. Round | 14/01/2022 | Club Necaxa [U20] | - | CF Monterrey [U20] | 1:1 |  |
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| 14. Round | 27/01/2022 | Pumas UNAM [U20] | - | CF Monterrey [U20] | 4:0 | ||||
| 5. Round | 12/02/2022 | CF Monterrey [U20] | - | FC Juárez [U20] | 1:0 |  |
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| 6. Round | 18/02/2022 | Puebla FC [U20] | - | CF Monterrey [U20] | 3:0 | ||||
| 7. Round | 26/02/2022 | CF Monterrey [U20] | - | Atlético San Luis [U20] | 1:3 | ||||
| 8. Round | 01/03/2022 | Club León [U20] | - | CF Monterrey [U20] | 1:2 | ||||
| 17. Round | 30/04/2022 | CF Monterrey [U20] | - | Club Tijuana [U20] | 3:0 |
Mexico