| 9. Round | 02/09/2021 | Ecuador | - | Paraguay | 2:0 |  |
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| 6. Round | 05/09/2021 | Ecuador | - | Chile | 0:0 | ||||
| 10. Round | 09/09/2021 | Uruguay | - | Ecuador | 1:0 | ||||
| 11. Round | 08/10/2021 | Ecuador | - | Bolivia | 3:0 | ||||
| 5. Round | 10/10/2021 | Venezuela | - | Ecuador | 2:1 |  |
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| 12. Round | 14/10/2021 | Colombia | - | Ecuador | 0:0 | ||||
| 13. Round | 11/11/2021 | Ecuador | - | Venezuela | 1:0 | ||||
| 14. Round | 17/11/2021 | Chile | - | Ecuador | 0:2 | ||||
| 15. Round | 27/01/2022 | Ecuador | - | Brazil | 1:1 | |
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| 16. Round | 02/02/2022 | Peru | - | Ecuador | 1:1 | ||||
| 17. Round | 24/03/2022 | Paraguay | - | Ecuador | 3:1 | |
Ecuador