| 2. Round | 23/06/2021 | Deportes Melipilla | - | Ñublense | 0:1 | ||||
| 2. Round | 27/06/2021 | Ñublense | - | Deportes Melipilla | 0:0 | ||||
| Round of 16 | 01/07/2021 | Ñublense | - | O'Higgins | 1:1 | ||||
| Round of 16 | 04/07/2021 | O'Higgins | - | Ñublense | 2:3 pso | ||||
| Quarter-finals | 09/07/2021 | Everton | - | Ñublense | 1:0 | ||||
| Quarter-finals | 11/07/2021 | Ñublense | - | Everton | 1:1 |
Chile