| 1. Round | 08/08/2022 | FK Dukla Praha [Youth B] | - | AC Sparta Praha [Youth B] | 1:4 |  |
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| 2. Round | 13/08/2022 | FK Dukla Praha [Youth B] | - | MFK Karviná [Youth B] | 3:3 | |
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| 3. Round | 19/08/2022 | FK Příbram [Youth B] | - | FK Dukla Praha [Youth B] | 1:2 | |
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| 4. Round | 27/08/2022 | FK Dukla Praha [Youth B] | - | FC Zlín [Youth B] | 1:1 | ||||
| 8. Round | 30/08/2022 | FK Dukla Praha [Youth B] | - | Banik Ostrava [Youth B] | 0:6 | ||||
| 6. Round | 09/09/2022 | FK Dukla Praha [Youth B] | - | Vysočina Jihlava [Youth B] | 2:3 | |
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| 7. Round | 17/09/2022 | FK Pardubice [Youth B] | - | FK Dukla Praha [Youth B] | 4:1 | ||||
| 9. Round | 01/10/2022 | Dynamo České Budějovice [Youth B] | - | FK Dukla Praha [Youth B] | 4:0 | ||||
| 10. Round | 08/10/2022 | FK Dukla Praha [Youth B] | - | Sigma Olomouc [Youth B] | 0:1 | ||||
| 11. Round | 14/10/2022 | 1. FC Slovácko [Youth B] | - | FK Dukla Praha [Youth B] | 1:1 | |
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| 13. Round | 28/10/2022 | Viktoria Plzeň [Youth B] | - | FK Dukla Praha [Youth B] | 2:3 | |
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| 14. Round | 05/11/2022 | FC Zbrojovka Brno [Youth B] | - | FK Dukla Praha [Youth B] | 6:1 | ||||
| 15. Round | 12/11/2022 | Slavia Praha [Youth B] | - | FK Dukla Praha [Youth B] | 2:3 |
Czech Republic