| 6. Round | 19/02/2022 | FC Juárez | - | Santos Laguna | 0:0 | ||||
| 9. Round | 06/03/2022 | Deportivo Guadalajara | - | Santos Laguna | 1:0 | ||||
| 12. Round | 04/04/2022 | Santos Laguna | - | CF Pachuca | 3:1 |
| 6. Round | 19/02/2022 | FC Juárez | - | Santos Laguna | 0:0 | ||||
| 9. Round | 06/03/2022 | Deportivo Guadalajara | - | Santos Laguna | 1:0 | ||||
| 12. Round | 04/04/2022 | Santos Laguna | - | CF Pachuca | 3:1 |
| Franco Nicolás Pizzichillo Fernández | |
| Born: | 03.01.1996 |
| Place of birth: |
Paysandú, 
Uruguay |
| Nationality: |
Uruguay
Italy |
| Height: | 177 cm |
| Weight: | 70 kg |
| Position(s): | Right Back Defensive Midfielder |
| Foot: | right |