 |
 |
|
|
| 05/03/2022 | 01:00 | Club Necaxa | - | Deportivo Toluca | 0:1 (0:1) | |
| 03:00 | FC Juárez | - | Club León | 0:1 (0:0) | ||
| 23:00 | Gallos Blancos | - | Atlas Guadalajara | 0:3 dec. | ||
| 06/03/2022 | 01:06 | CF Monterrey | - | CF América | 2:1 (1:1) | |
| 03:00 | Deportivo Guadalajara | - | Santos Laguna | 1:0 (0:0) | ||
| 03:00 | Cruz Azul | - | Puebla FC | 1:3 (1:2) | ||
| 26/03/2022 | 23:00 | Pumas UNAM | - | Mazatlán FC | 1:1 (0:0) | |
| 07/04/2022 | 03:06 | Club Tijuana | - | Atlético San Luis | 1:1 (0:0) | |
| 08/04/2022 | 01:00 | CF Pachuca | - | UANL Tigres | 2:1 (0:0) |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CF Pachuca | 9 | 7 | 1 | 1 | 19:9 | 10 | 22 |
| 2 |
|
Puebla FC | 9 | 6 | 3 | 0 | 17:7 | 10 | 21 |
| 3 |
|
UANL Tigres | 9 | 5 | 2 | 2 | 18:15 | 3 | 17 |
| 4 |
|
Atlas Guadalajara | 9 | 4 | 3 | 2 | 10:6 | 4 | 15 |
| 5 |
|
Club León | 9 | 4 | 3 | 2 | 9:7 | 2 | 15 |
| 6 |
|
Cruz Azul | 9 | 4 | 2 | 3 | 15:12 | 3 | 14 |
| 7 |
|
Deportivo Toluca | 9 | 4 | 2 | 3 | 12:16 | -4 | 14 |
| 8 |
|
CF Monterrey | 9 | 3 | 4 | 2 | 13:8 | 5 | 13 |
| 9 |
|
Pumas UNAM | 9 | 3 | 3 | 3 | 14:9 | 5 | 12 |
| 10 |
|
Club Tijuana | 9 | 3 | 3 | 3 | 9:11 | -2 | 12 |
| 11 |
|
Deportivo Guadalajara | 9 | 3 | 2 | 4 | 15:14 | 1 | 11 |
| 12 |
|
Atlético San Luis | 9 | 2 | 2 | 5 | 9:12 | -3 | 8 |
| 13 |
|
Club Necaxa | 9 | 2 | 2 | 5 | 9:14 | -5 | 8 |
| 14 |
|
Gallos Blancos | 9 | 1 | 5 | 3 | 8:13 | -5 | 8 |
| 15 |
|
Santos Laguna | 9 | 2 | 2 | 5 | 11:17 | -6 | 8 |
| 16 |
|
Mazatlán FC | 9 | 2 | 2 | 5 | 10:16 | -6 | 8 |
| 17 |
|
FC Juárez | 9 | 2 | 2 | 5 | 7:13 | -6 | 8 |
| 18 |
|
CF América | 9 | 1 | 3 | 5 | 10:16 | -6 | 6 |
| Playoffs | |
| Next Round |
