| 1. Round | 23/07/1988 | Neuchâtel Xamax FC | - | AC Bellinzona | 2:2 | ||||
| 5. Round | 10/08/1988 | Neuchâtel Xamax FC | - | BSC Young Boys | 2:5 | ||||
| 7. Round | 20/08/1988 | Neuchâtel Xamax FC | - | Servette FC | 2:1 | ||||
| 8. Round | 27/08/1988 | FC Lugano | - | Neuchâtel Xamax FC | 1:0 | ||||
| 9. Round | 30/08/1988 | Neuchâtel Xamax FC | - | FC Wettingen | 2:2 |  |
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| 11. Round | 14/09/1988 | FC Luzern | - | Neuchâtel Xamax FC | 1:0 | ||||
| 12. Round | 24/09/1988 | AC Bellinzona | - | Neuchâtel Xamax FC | 2:1 | ||||
| 14. Round | 08/10/1988 | FC St. Gallen | - | Neuchâtel Xamax FC | 3:3 | ||||
| 16. Round | 22/10/1988 | BSC Young Boys | - | Neuchâtel Xamax FC | 2:2 | ||||
| 17. Round | 29/10/1988 | Neuchâtel Xamax FC | - | Grasshopper Club Zürich | 4:0 | |
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| 18. Round | 03/11/1988 | Servette FC | - | Neuchâtel Xamax FC | 0:1 | ||||
| 19. Round | 19/11/1988 | Neuchâtel Xamax FC | - | FC Lugano | 5:1 | ||||
| 20. Round | 27/11/1988 | FC Wettingen | - | Neuchâtel Xamax FC | 2:0 | ||||
| 21. Round | 04/12/1988 | Lausanne Sports | - | Neuchâtel Xamax FC | 2:4 | |
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| 22. Round | 11/12/1988 | Neuchâtel Xamax FC | - | FC Luzern | 0:0 |
Switzerland