| 1. Round | 08/07/2022 | Patriotas FC | - | Atlético Junior | 1:0 | ||||
| 2. Round | 14/07/2022 | Atlético Junior | - | Atlético Nacional | 3:1 | ||||
| 3. Round | 17/07/2022 | La Equidad | - | Atlético Junior | 0:0 |  |
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| 4. Round | 24/07/2022 | Atlético Junior | - | Santa Fe | 2:0 | ||||
| 5. Round | 31/07/2022 | Águilas Doradas | - | Atlético Junior | 1:1 | ||||
| 6. Round | 08/08/2022 | Atlético Junior | - | Once Caldas | 1:2 | ||||
| 8. Round | 21/08/2022 | América de Cali | - | Atlético Junior | 2:1 |
Colombia