| 1. Round | 21/08/2021 | FC Gossau | - | FC St. Gallen II | 1:0 | ||||
| 5. Round | 18/09/2021 | FC Gossau | - | FC Tuggen | 2:0 | ||||
| 6. Round | 25/09/2021 | FC Linth 04 | - | FC Gossau | 1:0 | ||||
| 7. Round | 02/10/2021 | FC Gossau | - | USV Eschen/Mauren | 0:4 | ||||
| 8. Round | 16/10/2021 | FC Thalwil | - | FC Gossau | 3:2 | ||||
| 9. Round | 23/10/2021 | FC Gossau | - | FC Lugano II | 5:3 | ||||
| 10. Round | 30/10/2021 | FC Gossau | - | FC Baden | 3:3 | ||||
| 11. Round | 06/11/2021 | FC Wettswil-Bonstetten | - | FC Gossau | 2:1 | ||||
| 12. Round | 13/11/2021 | FC Gossau | - | FC Paradiso | 2:3 | ||||
| 13. Round | 20/11/2021 | FC Freienbach | - | FC Gossau | 4:0 | ||||
| 14. Round | 28/11/2021 | FC St. Gallen II | - | FC Gossau | 6:1 | ||||
| 15. Round | 05/03/2022 | FC Gossau | - | FC Winterthur II | 1:5 | ||||
| 17. Round | 19/03/2022 | FC Gossau | - | FC Balzers | 1:3 | ||||
| 22. Round | 01/05/2022 | FC Lugano II | - | FC Gossau | 1:0 | ||||
| 25. Round | 21/05/2022 | FC Paradiso | - | FC Gossau | 1:4 | ||||
| 26. Round | 28/05/2022 | FC Gossau | - | FC Freienbach | 3:2 |  |
Switzerland