| Group E | 14/09/2021 | Dinamo Kiev | - | SL Benfica | 0:0 | ||||
| Group E | 29/09/2021 | SL Benfica | - | FC Barcelona | 3:0 | ||||
| Group E | 02/11/2021 | Bayern München | - | SL Benfica | 5:2 | ||||
| Group E | 23/11/2021 | FC Barcelona | - | SL Benfica | 0:0 | ||||
| Group E | 08/12/2021 | SL Benfica | - | Dinamo Kiev | 2:0 |  |
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| Round of 16 | 23/02/2022 | SL Benfica | - | AFC Ajax | 2:2 | ||||
| Round of 16 | 15/03/2022 | AFC Ajax | - | SL Benfica | 0:1 | ||||
| Quarter-finals | 05/04/2022 | SL Benfica | - | Liverpool FC | 1:3 | ||||
| Quarter-finals | 13/04/2022 | Liverpool FC | - | SL Benfica | 3:3 |
Brazil