| 1. Round | 23/08/1980 | CS Chênois | - | FC Chiasso | 1:1 | ||||
| 5. Round | 20/09/1980 | CS Chênois | - | Servette FC | 2:2 | ||||
| 6. Round | 04/10/1980 | FC Luzern | - | CS Chênois | 2:1 | ||||
| 7. Round | 08/10/1980 | FC St. Gallen | - | CS Chênois | 2:0 | ||||
| 8. Round | 11/10/1980 | CS Chênois | - | AC Bellinzona | 2:1 | ||||
| 9. Round | 18/10/1980 | FC Nordstern Basel | - | CS Chênois | 1:2 |  |
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| 10. Round | 25/10/1980 | CS Chênois | - | Lausanne Sports | 1:4 | ||||
| 11. Round | 15/11/1980 | BSC Young Boys | - | CS Chênois | 1:1 | |
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| 12. Round | 22/11/1980 | CS Chênois | - | Grasshopper Club Zürich | 1:3 | ||||
| 13. Round | 07/12/1980 | CS Chênois | - | FC Zürich | 1:3 | ||||
| 18. Round | 05/04/1981 | Servette FC | - | CS Chênois | 3:1 | ||||
| 20. Round | 25/04/1981 | AC Bellinzona | - | CS Chênois | 3:1 |
Switzerland