| 4. Round | 07/08/2022 | FK Sochi | - | FK Nizhny Novgorod | 2:1 | ||||
| 5. Round | 14/08/2022 | FK Nizhny Novgorod | - | FK Rostov | 3:4 | ||||
| 6. Round | 20/08/2022 | FK Ural | - | FK Nizhny Novgorod | 0:1 |  |
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| 7. Round | 27/08/2022 | FK Nizhny Novgorod | - | Dinamo Moskva | 2:2 | |
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| 8. Round | 03/09/2022 | FK Nizhny Novgorod | - | Fakel Voronezh | 3:1 | |
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| 9. Round | 10/09/2022 | Akhmat Grozny | - | FK Nizhny Novgorod | 1:3 | ||||
| 10. Round | 18/09/2022 | FK Nizhny Novgorod | - | FK Orenburg | 0:2 | ||||
| 11. Round | 02/10/2022 | FK Nizhny Novgorod | - | Spartak Moskva | 1:2 | ||||
| 12. Round | 09/10/2022 | Torpedo Moskva | - | FK Nizhny Novgorod | 0:0 | |
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| 14. Round | 22/10/2022 | FK Nizhny Novgorod | - | FK Krasnodar | 0:2 | ||||
| 15. Round | 30/10/2022 | Krylia Sovetov | - | FK Nizhny Novgorod | 2:1 | ||||
| 16. Round | 05/11/2022 | CSKA Moskva | - | FK Nizhny Novgorod | 0:1 | ||||
| 17. Round | 11/11/2022 | FK Nizhny Novgorod | - | Akhmat Grozny | 3:2 |
Russia