| 1. Round | 07/08/2021 | Tauro FC | - | Plaza Amador | 0:0 | ||||
| 2. Round | 14/08/2021 | Árabe Unido | - | Tauro FC | 0:1 |  |
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| 3. Round | 21/08/2021 | Sporting San Miguelito | - | Tauro FC | 1:0 | ||||
| 4. Round | 29/08/2021 | Tauro FC | - | Alianza | 0:0 | ||||
| 5. Round | 04/09/2021 | Costa del Este | - | Tauro FC | 1:2 | |
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| 6. Round | 12/09/2021 | San Francisco FC | - | Tauro FC | 1:3 | |
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| 7. Round | 19/09/2021 | Atlético Chiriquí | - | Tauro FC | 0:1 | ||||
| 8. Round | 26/09/2021 | Tauro FC | - | Herrera FC | 1:1 | ||||
| 9. Round | 03/10/2021 | Tauro FC | - | UD Universitario | 3:1 | |
Panama
