| 1. Round | 22/08/2021 | Paris Saint-Germain [Youth] | - | FC Chambly [Youth] | 3:1 |  |
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| 2. Round | 28/08/2021 | Valenciennes FC [Youth] | - | Paris Saint-Germain [Youth] | 2:3 | ||||
| 7. Round | 03/10/2021 | Paris Saint-Germain [Youth] | - | Lille OSC [Youth] | 2:1 | ||||
| 10. Round | 24/10/2021 | JA Drancy [Youth] | - | Paris Saint-Germain [Youth] | 3:3 |  |
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| 12. Round | 21/11/2021 | Paris Saint-Germain [Youth] | - | Havre AC [Youth] | 3:0 | |
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| 13. Round | 28/11/2021 | SM Caen [Youth] | - | Paris Saint-Germain [Youth] | 0:3 | |
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| 14. Round | 04/12/2021 | Paris Saint-Germain [Youth] | - | Valenciennes FC [Youth] | 8:0 | |
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| 15. Round | 16/01/2022 | US Orléans [Youth] | - | Paris Saint-Germain [Youth] | 0:2 | ||||
| 16. Round | 23/01/2022 | Paris Saint-Germain [Youth] | - | RC Lens [Youth] | 6:0 | ||||
| 18. Round | 13/02/2022 | St-Pryvé St-Hilaire [Youth] | - | Paris Saint-Germain [Youth] | 1:4 | ||||
| 19. Round | 06/03/2022 | Lille OSC [Youth] | - | Paris Saint-Germain [Youth] | 1:1 | ||||
| 20. Round | 20/03/2022 | Paris Saint-Germain [Youth] | - | Entente Feignies Aulnoye [Youth] | 4:1 | |
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| 25. Round | 01/05/2022 | Paris Saint-Germain [Youth] | - | SM Caen [Youth] | 4:1 | |
France