| 4. Round | 24/11/2021 | Almopos Arideas | - | Pierikos Katerini | 3:1 | ||||
| 5. Round | 28/11/2021 | Xanthi FC | - | Almopos Arideas | 2:0 | ||||
| 6. Round | 05/12/2021 | Almopos Arideas | - | Thesprotos | 1:0 | ||||
| 14. Round | 16/01/2022 | Apollon Lárissa | - | Almopos Arideas | 1:1 | ||||
| 20. Round | 20/02/2022 | Almopos Arideas | - | Anagennisi Karditsa | 1:0 |  |
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| 23. Round | 09/03/2022 | Thesprotos | - | Almopos Arideas | 0:3 | ||||
| 24. Round | 13/03/2022 | Almopos Arideas | - | AO Kavala | 1:1 | ||||
| 26. Round | 26/03/2022 | Niki Volou FC | - | Almopos Arideas | 1:0 | ||||
| 28. Round | 02/04/2022 | PAOK Saloniki II | - | Almopos Arideas | 0:1 | ||||
| 29. Round | 06/04/2022 | Almopos Arideas | - | AO Trikala | 3:0 | ||||
| 32. Round | 16/04/2022 | Olympiakos Piraeus II | - | Almopos Arideas | 2:1 | ||||
| 34. Round | 01/05/2022 | AEP Iraklis FC | - | Almopos Arideas | 6:0 |
Serbia