| 1. Round | 06/08/2022 | FK Pardubice [Youth B] | - | Sigma Olomouc [Youth B] | 1:2 | ||||
| 2. Round | 13/08/2022 | 1. FC Slovácko [Youth B] | - | FK Pardubice [Youth B] | 3:1 | ||||
| 3. Round | 19/08/2022 | FK Pardubice [Youth B] | - | FK Mladá Boleslav [Youth B] | 2:1 | ||||
| 4. Round | 27/08/2022 | Viktoria Plzeň [Youth B] | - | FK Pardubice [Youth B] | 3:2 | ||||
| 5. Round | 03/09/2022 | FK Pardubice [Youth B] | - | FC Zbrojovka Brno [Youth B] | 6:1 | ||||
| 7. Round | 17/09/2022 | FK Pardubice [Youth B] | - | FK Dukla Praha [Youth B] | 4:1 | ||||
| 9. Round | 01/10/2022 | FK Pardubice [Youth B] | - | FK Příbram [Youth B] | 11:0 | ||||
| 10. Round | 08/10/2022 | FC Zlín [Youth B] | - | FK Pardubice [Youth B] | 1:3 | ||||
| 11. Round | 14/10/2022 | FK Pardubice [Youth B] | - | FC Hradec Králové [Youth B] | 1:2 | ||||
| 12. Round | 22/10/2022 | Vysočina Jihlava [Youth B] | - | FK Pardubice [Youth B] | 1:3 | ||||
| 13. Round | 29/10/2022 | FK Pardubice [Youth B] | - | AC Sparta Praha [Youth B] | 4:2 | ||||
| 14. Round | 05/11/2022 | FK Pardubice [Youth B] | - | Banik Ostrava [Youth B] | 1:2 | ||||
| 15. Round | 12/11/2022 | Dynamo České Budějovice [Youth B] | - | FK Pardubice [Youth B] | 3:5 |
Czech Republic