| 1. Round | 20/08/2022 | Meteor Praha VIII [Youth C] | - | Slavia Praha [Youth C] | 1:5 |  |
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| 2. Round | 28/08/2022 | Slavia Praha [Youth C] | - | FK Pardubice [Youth C] | 6:4 | |
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| 5. Round | 17/09/2022 | Slovan Liberec [Youth C] | - | Slavia Praha [Youth C] | 0:10 | |
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| 7. Round | 28/09/2022 | FK Jablonec [Youth C] | - | Slavia Praha [Youth C] | 0:9 | |
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| 9. Round | 16/10/2022 | Bohemians Praha 1905 [Youth C] | - | Slavia Praha [Youth C] | 2:2 | ||||
| 10. Round | 23/10/2022 | Slavia Praha [Youth C] | - | FK Teplice [Youth C] | 7:1 | |
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| 12. Round | 05/11/2022 | Slavia Praha [Youth C] | - | RMSK Nový Bydžov [Youth C] | 4:0 | ||||
| 13. Round | 13/11/2022 | AC Sparta Praha [Youth C] | - | Slavia Praha [Youth C] | 4:4 | |
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| 11. Round | 19/11/2022 | Viktoria Plzeň [Youth C] | - | Slavia Praha [Youth C] | 3:2 | |
Czech Republic