| 18. Round | 07/02/2021 | FK Teplice | - | FK Pardubice | 0:1 | ||||
| 19. Round | 12/02/2021 | 1. FC Slovácko | - | FK Teplice | 2:0 | ||||
| 20. Round | 21/02/2021 | FK Teplice | - | Slavia Praha | 1:1 | ||||
| 21. Round | 27/02/2021 | Baník Ostrava | - | FK Teplice | 1:1 | ||||
| 22. Round | 06/03/2021 | FK Teplice | - | SFC Opava | 3:1 | ||||
| 23. Round | 12/03/2021 | Slovan Liberec | - | FK Teplice | 2:1 | ||||
| 24. Round | 21/03/2021 | FK Teplice | - | Bohemians Praha 1905 | 1:1 | ||||
| 26. Round | 11/04/2021 | FK Teplice | - | FK Mladá Boleslav | 1:3 |  |
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| 27. Round | 17/04/2021 | Sigma Olomouc | - | FK Teplice | 1:1 | ||||
| 28. Round | 21/04/2021 | FK Teplice | - | Viktoria Plzeň | 0:1 |
Czech Republic