| 1. Round | 08/01/2021 | Club Tijuana [U20] | - | Pumas UNAM [U20] | 4:1 | ||||
| 2. Round | 15/01/2021 | FC Juárez [U20] | - | Club Tijuana [U20] | 1:0 | ||||
| 3. Round | 22/01/2021 | Puebla FC [U20] | - | Club Tijuana [U20] | 0:2 | ||||
| 10. Round | 08/03/2021 | CF Pachuca [U20] | - | Club Tijuana [U20] | 3:2 | ||||
| 13. Round | 03/04/2021 | Atlas Guadalajara [U20] | - | Club Tijuana [U20] | 0:1 | ||||
| 14. Round | 11/04/2021 | Club Tijuana [U20] | - | Mazatlán FC [U20] | 1:0 | ||||
| 15. Round | 17/04/2021 | Deportivo Guadalajara [U20] | - | Club Tijuana [U20] | 2:1 | ||||
| 16. Round | 23/04/2021 | Club Tijuana [U20] | - | Club Necaxa [U20] | 3:1 | ||||
| 17. Round | 01/05/2021 | Cruz Azul [U20] | - | Club Tijuana [U20] | 0:1 |
Mexico