| 3. Round | 28/08/2005 | Karlsruher SC | - | Wacker Burghausen | 0:1 | ||||
| 11. Round | 30/10/2005 | SpVgg Greuther Fürth | - | Karlsruher SC | 3:1 | ||||
| 13. Round | 18/11/2005 | Kickers Offenbach | - | Karlsruher SC | 1:3 | ||||
| 21. Round | 10/02/2006 | Karlsruher SC | - | Erzgebirge Aue | 5:2 | ||||
| 22. Round | 17/02/2006 | Karlsruher SC | - | SC Freiburg | 1:1 | ||||
| 23. Round | 26/02/2006 | SpVgg Unterhaching | - | Karlsruher SC | 4:1 | ||||
| 25. Round | 12/03/2006 | Energie Cottbus | - | Karlsruher SC | 0:0 | ||||
| 24. Round | 16/03/2006 | Karlsruher SC | - | 1. FC Saarbrücken | 2:1 | ||||
| 26. Round | 19/03/2006 | Karlsruher SC | - | LR Ahlen | 3:1 |  |
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| 27. Round | 26/03/2006 | Hansa Rostock | - | Karlsruher SC | 2:0 | ||||
| 28. Round | 31/03/2006 | Karlsruher SC | - | SpVgg Greuther Fürth | 2:1 | |
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| 29. Round | 10/04/2006 | Dynamo Dresden | - | Karlsruher SC | 3:2 | |
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| 30. Round | 13/04/2006 | Karlsruher SC | - | Kickers Offenbach | 1:1 |
Czech Republic