| 2. Round | 11/09/2021 | FC Schaffhausen [Youth B] | - | FC Rapperswil-Jona/GC [U18] | 1:6 | ||||
| 3. Round | 18/09/2021 | Team FC Luzern/SC Kriens [Youth B] | - | FC Schaffhausen [Youth B] | 4:1 | ||||
| 4. Round | 25/09/2021 | FC Schaffhausen [Youth B] | - | FC Basel 1893 [Youth B] | 1:6 | ||||
| 5. Round | 09/10/2021 | FC Concordia/FC Solothurn [U18] | - | FC Schaffhausen [Youth B] | 5:1 | ||||
| 6. Round | 16/10/2021 | FC Schaffhausen [Youth B] | - | BSC Young Boys [Youth B] | 1:6 | ||||
| 7. Round | 30/10/2021 | Team Vaud Lausanne [Youth B] | - | FC Schaffhausen [Youth B] | 2:2 | ||||
| 8. Round | 06/11/2021 | FC Schaffhausen [Youth B] | - | Team Liechtenstein [U18] | 2:2 | ||||
| 9. Round | 13/11/2021 | Servette FC [Youth B] | - | FC Schaffhausen [Youth B] | 4:2 |  |
Switzerland