| 1. Round | 13/02/2021 | Vélez Sarsfield | - | Newell's Old Boys | 1:0 |  |
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| 2. Round | 21/02/2021 | Sarmiento de Junín | - | Vélez Sarsfield | 1:2 | ||||
| 3. Round | 27/02/2021 | Argentinos Juniors | - | Vélez Sarsfield | 0:2 |  |
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| 4. Round | 08/03/2021 | Vélez Sarsfield | - | Boca Juniors | 1:7 | |
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| 5. Round | 13/03/2021 | Talleres de Córdoba | - | Vélez Sarsfield | 0:1 | ||||
| 6. Round | 20/03/2021 | Vélez Sarsfield | - | Independiente | 1:0 | ||||
| 7. Round | 28/03/2021 | Defensa y Justicia | - | Vélez Sarsfield | 1:1 | ||||
| 8. Round | 04/04/2021 | Vélez Sarsfield | - | Unión de Santa Fe | 4:1 | |
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| 9. Round | 13/04/2021 | Atlético Tucumán | - | Vélez Sarsfield | 2:0 | ||||
| 10. Round | 16/04/2021 | Vélez Sarsfield | - | Huracán | 2:0 | |
Argentina